Cargando…
Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target
Progression of chronic lymphocytic leukemia (CLL) results from the expansion of a small fraction of proliferating leukemic B cells. When comparing the global gene expression of recently divided CLL cells with that of previously divided cells, we found higher levels of genes involved in regulating ge...
Autores principales: | Palacios, Florencia, Yan, Xiao-Jie, Ferrer, Gerardo, Chen, Shih-Shih, Vergani, Stefano, Yang, Xuejing, Gardner, Jeffrey, Barrientos, Jaqueline C., Rock, Philip, Burack, Richard, Kolitz, Jonathan E., Allen, Steven L., Kharas, Michael G., Abdel-Wahab, Omar, Rai, Kanti R., Chiorazzi, Nicholas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024198/ https://www.ncbi.nlm.nih.gov/pubmed/33504942 http://dx.doi.org/10.1038/s41375-020-01115-y |
Ejemplares similares
-
A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice
por: Patten, Piers E. M., et al.
Publicado: (2021) -
CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: Apparent lack of central and early peripheral tolerance censoring
por: Vergani, Stefano, et al.
Publicado: (2023) -
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL
por: Ferrer, Gerardo, et al.
Publicado: (2021) -
Identification and characterization of distinct IL-17F expression patterns and signaling pathways in chronic lymphocytic leukemia and normal B lymphocytes
por: Sherry, Barbara, et al.
Publicado: (2015) -
RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
por: Montalbano, Mauro, et al.
Publicado: (2020)