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The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

Despite the importance of immunity against neuraminidase (NA), NA content and immunogenicity are neglected in current influenza vaccines. To address this, a recombinant N1/N2 NA vaccine (NAV) was developed. Stability assays were used to determine optimal temperature and buffer conditions for vaccine...

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Detalles Bibliográficos
Autores principales: Giurgea, Luca T., Park, Jae-Keun, Walters, Kathie-Anne, Scherler, Kelsey, Cervantes-Medina, Adriana, Freeman, Ashley, Rosas, Luz Angela, Kash, John C., Taubenberger, Jeffery K., Memoli, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024250/
https://www.ncbi.nlm.nih.gov/pubmed/33824333
http://dx.doi.org/10.1038/s41541-021-00310-x