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Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase
Human manganese superoxide dismutase is a critical oxidoreductase found in the mitochondrial matrix. Concerted proton and electron transfers are used by the enzyme to rid the mitochondria of O(2)(•−). The mechanisms of concerted transfer enzymes are typically unknown due to the difficulties in detec...
Autores principales: | Azadmanesh, Jahaun, Lutz, William E., Coates, Leighton, Weiss, Kevin L., Borgstahl, Gloria E. O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024262/ https://www.ncbi.nlm.nih.gov/pubmed/33824320 http://dx.doi.org/10.1038/s41467-021-22290-1 |
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