Cargando…

ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells

As a result of mutations in the upstream components of the Wnt/β-catenin signaling pathway, this cascade is abnormally activated in colon cancer. Hence, identifying the activation mechanism of this pathway is an urgent need for the treatment of colon cancer. Here, we found an increase in ADCK1 (AarF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Yong, Liu, Yiqian, Sun, Changchun, Yu, Lijiang, Wang, Zhao, Du, Xu, Yang, Wu, Zhang, Chenggong, Tao, Chunmu, Wang, Jianjiang, Yang, Xi, Di, Sun, Huang, Yufeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024291/ https://www.ncbi.nlm.nih.gov/pubmed/33824271 http://dx.doi.org/10.1038/s41419-021-03624-9

Ejemplares similares

ADCK2 Knockdown Affects the Migration of Melanoma Cells via MYL6
por: Vierthaler, Marlene, et al.
Publicado: (2022)

Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
por: Gan, Xiao-qing, et al.
Publicado: (2008)

ADCK1 is a potential therapeutic target of osteosarcoma
por: Zhuo, Bao-biao, et al.
Publicado: (2022)

Identification of the mitochondrial protein ADCK2 as a therapeutic oncotarget of NSCLC
por: Zhang, Jin-zhi, et al.
Publicado: (2022)

Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle
por: Yoon, Woongchang, et al.
Publicado: (2019)

Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells
por: Dai, Yuedi, et al.
Publicado: (2016)

NDRG2 expression decreases with tumor stages and regulates TCF/β-catenin signaling in human colon carcinoma
por: Kim, Young-Jun, et al.
Publicado: (2009)

Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10
por: Li, Nan, et al.
Publicado: (2015)

Suppression of neointima formation by targeting β-catenin/TCF pathway
por: Williams, Helen, et al.
Publicado: (2016)

NOP7 interacts with β-catenin and activates β-catenin/TCF signaling in hepatocellular carcinoma cells
por: Wu, Nan, et al.
Publicado: (2018)

MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling
por: Sun, Jikui, et al.
Publicado: (2017)

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain
por: Wisniewska, Marta B.
Publicado: (2013)

Inhibitor of β-catenin and TCF (ICAT) promotes cervical cancer growth and metastasis by disrupting E-cadherin/β-catenin complex
por: Jiang, Yayun, et al.
Publicado: (2017)

FOXM 1 induces Vasculogenic mimicry in esophageal cancer through β-catenin /Tcf4 signaling
por: Cheng, Lili, et al.
Publicado: (2020)

Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity
por: Li, Nan, et al.
Publicado: (2014)

Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
por: He, Mudan, et al.
Publicado: (2020)

Physiological regulation of β-catenin stability by Tcf3 and CK1ε
por: Lee, Ethan, et al.
Publicado: (2001)

TCF/β-catenin plays an important role in HCCR-1 oncogene expression
por: Cho, Goang-Won, et al.
Publicado: (2009)

VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry
por: Delgado-Bellido, Daniel, et al.
Publicado: (2023)

Early-onset of ADCK4 glomerulopathy with renal failure: a case report
por: Lolin, Ksenija, et al.
Publicado: (2017)

Calorie Restriction Rescues Mitochondrial Dysfunction in Adck2-Deficient Skeletal Muscle
por: Hernández-Camacho, Juan Diego, et al.
Publicado: (2022)

Axin downregulates TCF-4 transcription via β-catenin, but not p53, and inhibits the proliferation and invasion of lung cancer cells
por: Yang, Lian-He, et al.
Publicado: (2010)

β-Catenin/Tcf7l2–dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer
por: Zhao, Zibo, et al.
Publicado: (2019)

Thermostable Direct Hemolysin Downregulates Human Colon Carcinoma Cell Proliferation with the Involvement of E-Cadherin, and β-Catenin/Tcf-4 Signaling
por: Chowdhury, Pinki, et al.
Publicado: (2011)

Bufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase
por: Yu, Zhuo, et al.
Publicado: (2018)

TCF7 knockdown inhibits the imatinib resistance of chronic myeloid leukemia K562/G01 cells by neutralizing the Wnt/β-catenin/TCF7/ABC transporter signaling axis
por: Zhang, Hui, et al.
Publicado: (2021)

Past Visits Present: TCF/LEFs Partner with ATFs for β-Catenin–Independent Activity
por: Sprowl, Stephanie, et al.
Publicado: (2013)

Quantitative Differences in Nuclear β-catenin and TCF Pattern Embryonic Cells in C. elegans
por: Zacharias, Amanda L., et al.
Publicado: (2015)

Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer
por: Schneider, Jeffrey A., et al.
Publicado: (2018)

The β-catenin/TCF-4 pathway regulates the expression of OPN in human osteoarthritic chondrocytes
por: Tian, Jian, et al.
Publicado: (2020)

Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
por: Low, Joo-Leng, et al.
Publicado: (2021)

Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression
por: Wallmen, Britta, et al.
Publicado: (2012)

CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma
por: Fan, Xin, et al.
Publicado: (2016)

VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
por: Zhang, Haifeng, et al.
Publicado: (2021)

Geniposide promotes beta-cell regeneration and survival through regulating β-catenin/TCF7L2 pathway
por: Yao, D D, et al.
Publicado: (2015)

Down-regulation of E-cadherin is an essential event in activating β-catenin/Tcf dependent transcription and expression of its target genes in Pdcd4 knock-down cells
por: Wang, Qing, et al.
Publicado: (2009)

Ginsenoside Rb1 Lessens Gastric Precancerous Lesions by Interfering With β-Catenin/TCF4 Interaction
por: Zeng, Jinhao, et al.
Publicado: (2021)

Tcf-3 expression and β -catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour)
por: Tejpar, S, et al.
Publicado: (2001)

Securin (hPTTG1) expression is regulated by β-catenin/TCF in human colorectal carcinoma
por: Hlubek, F, et al.
Publicado: (2006)

HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction
por: Ye, Feng, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_fmrreov82riksq76nqkstb8keg