Epitope-directed monoclonal antibody production using a mixed antigen cocktail facilitates antibody characterization and validation

High quality, well-validated antibodies are needed to mitigate irreproducibility and clarify conflicting data in science. We describe an epitope-directed monoclonal antibody (mAb) production method that addresses issues of antibody quality, validation and utility. The workflow is illustrated by gene...

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Detalles Bibliográficos
Autores principales: Liew, Oi Wah, Ling, Samantha S. M., Lilyanna, Shera, Zhou, Yue, Wang, Peipei, Chong, Jenny P. C., Ng, Yan Xia, Lim, Angeline E. S., Leong, Eliot R. Y., Lin, Qifeng, Lim, Teck Kwang, Lin, Qingsong, Ng, Enoch M. W., Ng, Tuck Wah, Richards, A. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024308/
https://www.ncbi.nlm.nih.gov/pubmed/33824395
http://dx.doi.org/10.1038/s42003-021-01965-x

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