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Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia
Lipocalin 2 (LCN2) was recently identified as an endogenous ligand of the type 4 melanocortin receptor (MC4R), a critical regulator of appetite. However, it remains unknown if this molecule influences appetite during cancer cachexia, a devastating clinical entity characterized by decreased nutrition...
Autores principales: | Olson, Brennan, Zhu, Xinxia, Norgard, Mason A., Levasseur, Peter R., Butler, John T., Buenafe, Abigail, Burfeind, Kevin G., Michaelis, Katherine A., Pelz, Katherine R., Mendez, Heike, Edwards, Jared, Krasnow, Stephanie M., Grossberg, Aaron J., Marks, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024334/ https://www.ncbi.nlm.nih.gov/pubmed/33824339 http://dx.doi.org/10.1038/s41467-021-22361-3 |
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