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Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling
Wnt signaling regulates cell proliferation and cell differentiation as well as migration and polarity during development. However, it is still unclear how the Wnt ligand distribution is precisely controlled to fulfil these functions. Here, we show that the planar cell polarity protein Vangl2 regulat...
Autores principales: | Brunt, Lucy, Greicius, Gediminas, Rogers, Sally, Evans, Benjamin D., Virshup, David M., Wedgwood, Kyle C. A., Scholpp, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024337/ https://www.ncbi.nlm.nih.gov/pubmed/33824332 http://dx.doi.org/10.1038/s41467-021-22393-9 |
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