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Membrane lymphotoxin-α(2)β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist
In the early 1990s, it has been described that LTα and LTβ form LTα(2)β and LTαβ(2) heterotrimers, which bind to TNFR1 and LTβR, respectively. Afterwards, the LTαβ(2)–LTβR system has been intensively studied while the LTα(2)β–TNFR1 interaction has been ignored to date, presumably due to the fact tha...
Autores principales: | Kucka, Kirstin, Lang, Isabell, Zhang, Tengyu, Siegmund, Daniela, Medler, Juliane, Wajant, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024344/ https://www.ncbi.nlm.nih.gov/pubmed/33824270 http://dx.doi.org/10.1038/s41419-021-03633-8 |
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