Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

Loss of TP53 and RB1 in treatment-naïve small cell lung cancer (SCLC) suggests selective pressure to inactivate cell death pathways prior to therapy. Yet, which of these pathways remain available in treatment-naïve SCLC is unknown. Here, through systemic analysis of cell death pathway availability i...

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Detalles Bibliográficos
Autores principales: Bebber, Christina M., Thomas, Emily S., Stroh, Jenny, Chen, Zhiyi, Androulidaki, Ariadne, Schmitt, Anna, Höhne, Michaela N., Stüker, Lukas, de Pádua Alves, Cleidson, Khonsari, Armin, Dammert, Marcel A., Parmaksiz, Fatma, Tumbrink, Hannah L., Beleggia, Filippo, Sos, Martin L., Riemer, Jan, George, Julie, Brodesser, Susanne, Thomas, Roman K., Christian Reinhardt, H., von Karstedt, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024350/
https://www.ncbi.nlm.nih.gov/pubmed/33824345
http://dx.doi.org/10.1038/s41467-021-22336-4

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