CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo

CARD-CC complexes involving BCL10 and MALT1 are major cellular signaling hubs. They govern NF-κB activation through their scaffolding properties as well as MALT1 paracaspase function, which cleaves substrates involved in NF-κB regulation. In human lymphocytes, gain-of-function defects in this pathwa...

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Detalles Bibliográficos
Autores principales: Israël, Laura, Glück, Anton, Berger, Marjorie, Coral, Marine, Ceci, Melanie, Unterreiner, Adeline, Rubert, Joëlle, Bardet, Maureen, Ginster, Stefanie, Golding-Ochsenbein, Alexandra M., Martin, Kea, Hoyler, Thomas, Calzascia, Thomas, Wieczorek, Grazyna, Hillenbrand, Rainer, Ferretti, Stéphane, Ferrero, Enrico, Bornancin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024357/
https://www.ncbi.nlm.nih.gov/pubmed/33824280
http://dx.doi.org/10.1038/s41389-021-00321-2

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