Cargando…

Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes

Stem cell niche is regulated by intrinsic and extrinsic factors. In the Drosophila testis, cyst stem cells (CySCs) support the differentiation of germline stem cells (GSCs). However, the underlying mechanisms remain unclear. In this study, we found that somatic CG6015 is required for CySC maintenanc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Qianwen, Chen, Xia, Qiao, Chen, Wang, Min, Chen, Wanyin, Luan, Xiaojin, Yan, Yidan, Shen, Cong, Fang, Jie, Hu, Xing, Zheng, Bo, Wu, Yibo, Yu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024382/ https://www.ncbi.nlm.nih.gov/pubmed/33824283 http://dx.doi.org/10.1038/s41420-021-00452-w

Ejemplares similares

RpS13 controls the homeostasis of germline stem cell niche through Rho1‐mediated signals in the Drosophila testis
por: Wang, Min, et al.
Publicado: (2020)

CG6015 controls spermatogonia transit-amplifying divisions by epidermal growth factor receptor signaling in Drosophila testes
por: Yu, Jun, et al.
Publicado: (2021)

CG8005 Mediates Transit-Amplifying Spermatogonial Divisions via Oxidative Stress in Drosophila Testes
por: Chen, Wanyin, et al.
Publicado: (2020)

Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes
por: Yu, Jun, et al.
Publicado: (2019)

Precursor RNA processing 3 is required for male fertility, and germline stem cell self-renewal and differentiation via regulating spliceosome function in Drosophila testes
por: Chen, Xia, et al.
Publicado: (2019)

Germline competent mesoderm: the substrate for vertebrate germline and somatic stem cells?
por: Savage, Aaron M., et al.
Publicado: (2021)

Heterochromatin components in germline stem cell maintenance
por: Xing, Yalan, et al.
Publicado: (2015)

Effects of N-acetylcysteine on CG8005 gene-mediated proliferation and apoptosis of Drosophila S2 embryonic cells
por: Chen, Wanyin, et al.
Publicado: (2023)

Gilgamesh is required for the maintenance of germline stem cells in Drosophila testis
por: Chen, Dongsheng, et al.
Publicado: (2017)

Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015
por: Kim, Jin-Hee, et al.
Publicado: (2019)

A Germline‐Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells
por: Zhang, Ru, et al.
Publicado: (2022)

Smad-Independent BMP Signaling in Somatic Cells Limits the Size of the Germline Stem Cell Pool
por: Tseng, Chen-Yuan, et al.
Publicado: (2018)

Silver nanoparticles disrupt germline stem cell maintenance in the Drosophila testis
por: Ong, Cynthia, et al.
Publicado: (2016)

Small Maf functions in the maintenance of germline stem cells in the Drosophila testis
por: Tan, Sharon Wui Sing, et al.
Publicado: (2017)

Plasticity of male germline stem cells and their applications in reproductive and regenerative medicine
por: Chen, Zheng, et al.
Publicado: (2015)

Biochemical clinical factors associated with missed abortion independent of maternal age: A retrospective study of 795 cases with missed abortion and 694 cases with normal pregnancy
por: Fang, Jie, et al.
Publicado: (2018)

A Germline‐Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells (Adv. Sci. 36/2022)
por: Zhang, Ru, et al.
Publicado: (2022)

dRTEL1 is essential for the maintenance of Drosophila male germline stem cells
por: Yang, Ying, et al.
Publicado: (2021)

G protein-coupled receptors in stem cell maintenance and somatic reprogramming to pluripotent or cancer stem cells
por: Choi, Hye Yeon, et al.
Publicado: (2015)

Non-autonomous regulation of germline stem cell proliferation by somatic MPK-1/MAPK activity in C. elegans
por: Robinson-Thiewes, Sarah, et al.
Publicado: (2021)

Prostaglandin signals from adult germline stem cells delay somatic aging of Caenorhabditis elegans
por: Lee, Hyun Ju, et al.
Publicado: (2019)

Redox Homeostasis Plays Important Roles in the Maintenance of the Drosophila Testis Germline Stem Cells
por: Tan, Sharon Wui Sing, et al.
Publicado: (2017)

Systematic re-analysis strategy of serum indices identifies alkaline phosphatase as a potential predictive factor for cervical cancer
por: Yu, Jun, et al.
Publicado: (2019)

Role of the Hedgehog Signaling Pathway in Regulating the Behavior of Germline Stem Cells
por: Li, Shiqin, et al.
Publicado: (2017)

Ovarian germline stem cells
por: Dunlop, Cheryl E, et al.
Publicado: (2014)

Germline stem cells in human
por: Cheng, Hanhua, et al.
Publicado: (2022)

Evidence for Chromatin-Remodeling Complex PBAP-Controlled Maintenance of the Drosophila Ovarian Germline Stem Cells
por: He, Jie, et al.
Publicado: (2014)

High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells
por: Pech, Matthew F., et al.
Publicado: (2015)

Defining the expression of piRNA and transposable elements in Drosophila ovarian germline stem cells and somatic support cells
por: Story, Benjamin, et al.
Publicado: (2019)

Evolution of CG Methylation Maintenance Machinery in Plants
por: Tirot, Louis, et al.
Publicado: (2021)

Enhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis
por: Feng, Lijuan, et al.
Publicado: (2017)

Effects of shikonin on the development of ovarian follicles and female germline stem cells
por: Ma, Shu-Xin, et al.
Publicado: (2021)

Female germline stem cells: aging and anti-aging
por: Hong, Wenli, et al.
Publicado: (2022)

Cyclin B3 Deficiency Impairs Germline Stem Cell Maintenance and Its Overexpression Delays Cystoblast Differentiation in Drosophila Ovary
por: Chen, Dongsheng, et al.
Publicado: (2018)

Editorial: Germline Development: From Germline Stem Cells to Gametes
por: Lee, Myon-Hee, et al.
Publicado: (2020)

Histone H3K9 Trimethylase Eggless Controls Germline Stem Cell Maintenance and Differentiation
por: Wang, Xiaoxi, et al.
Publicado: (2011)

A Krüppel-like factor is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians
por: Issigonis, Melanie, et al.
Publicado: (2022)

Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila
por: Sênos Demarco, Rafael, et al.
Publicado: (2022)

Correction To: Germline stem cells in human
por: Cheng, Hanhua, et al.
Publicado: (2022)

Role of GLD-3 in suppression of the germline stem cell fate.
por: Mohammad, Ariz, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8c6eb7q8vq8bvb9fo6knnndf5h