Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

An effective tumor vaccine vector that can rapidly display neoantigens is urgently needed. Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are qualified as immunoadjuvants. Here, we describe a versatile OMV-based vaccine platform to elicit a specific anti-tumor immu...

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Detalles Bibliográficos
Autores principales: Cheng, Keman, Zhao, Ruifang, Li, Yao, Qi, Yingqiu, Wang, Yazhou, Zhang, Yinlong, Qin, Hao, Qin, Yuting, Chen, Long, Li, Chen, Liang, Jie, Li, Yujing, Xu, Jiaqi, Han, Xuexiang, Anderson, Gregory J., Shi, Jian, Ren, Lei, Zhao, Xiao, Nie, Guangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024398/
https://www.ncbi.nlm.nih.gov/pubmed/33824314
http://dx.doi.org/10.1038/s41467-021-22308-8

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