Cargando…

Comprehensive Pathogen Identification, Antibiotic Resistance, and Virulence Genes Prediction Directly From Simulated Blood Samples and Positive Blood Cultures by Nanopore Metagenomic Sequencing

Bloodstream infection is a major cause of morbidity and mortality worldwide. We explored whether MinION nanopore sequencing could accelerate diagnosis, resistance, and virulence profiling prediction in simulated blood samples and blood cultures. One milliliter of healthy blood samples each from dire...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Menglan, Wu, Yarong, Kudinha, Timothy, Jia, Peiyao, Wang, Lei, Xu, Yingchun, Yang, Qiwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024499/ https://www.ncbi.nlm.nih.gov/pubmed/33841495 http://dx.doi.org/10.3389/fgene.2021.620009

Ejemplares similares

In vitro and in vivo Effect of Antimicrobial Agent Combinations Against Carbapenem-Resistant Klebsiella pneumoniae with Different Resistance Mechanisms in China
por: Liu, Enbo, et al.
Publicado: (2021)

Nanopore Sequencing in Blood Diseases: A Wide Range of Opportunities
por: Minervini, Crescenzio Francesco, et al.
Publicado: (2020)

An Improved In-house MALDI-TOF MS Protocol for Direct Cost-Effective Identification of Pathogens from Blood Cultures
por: Zhou, Menglan, et al.
Publicado: (2017)

Kodamaea ohmeri as an Emerging Human Pathogen: A Review and Update
por: Zhou, Menglan, et al.
Publicado: (2021)

Antimicrobial Susceptibility and Virulence of mcr-1-Positive Enterobacteriaceae in China, a Multicenter Longitudinal Epidemiological Study
por: Jiang, Bin, et al.
Publicado: (2020)

Metagenomic surveillance for bacterial tick-borne pathogens using nanopore adaptive sampling
por: Kipp, Evan J., et al.
Publicado: (2023)

Emergence of ST11-K47 and ST11-K64 hypervirulent carbapenem-resistant Klebsiella pneumoniae in bacterial liver abscesses from China: a molecular, biological, and epidemiological study
por: Yang, Qiwen, et al.
Publicado: (2020)

Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing
por: Taxt, Arne M., et al.
Publicado: (2020)

Nanopore and Illumina Genome Sequencing of Fusarium oxysporum f. sp. lini Strains of Different Virulence
por: Dvorianinova, Ekaterina M., et al.
Publicado: (2021)

Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis
por: Greninger, Alexander L., et al.
Publicado: (2015)

Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples
por: Ton, Kim N. T., et al.
Publicado: (2018)

Measurement and Comparison of Organic Compound Concentrations in Plasma, Whole Blood, and Dried Blood Spot Samples
por: Batterman, Stuart A., et al.
Publicado: (2016)

MDACP: A Pathogen Genome and Metagenome Analysis Cloud Platform
por: Han, Na, et al.
Publicado: (2020)

Non-Lethal Blood Sampling of Fish in the lab and Field With Methods for Dried Blood Plasma Spot Omic Analyses
por: Pollard, S, et al.
Publicado: (2022)

Application of metagenomic shotgun sequencing to detect vector-borne pathogens in clinical blood samples
por: Vijayvargiya, Prakhar, et al.
Publicado: (2019)

A framework for real-time monitoring, analysis and adaptive sampling of viral amplicon nanopore sequencing
por: Munro, Rory, et al.
Publicado: (2023)

Comprehensive Analysis of the Immune Cell Infiltration Landscape and Immune-Related Methylation in Retinoblastoma
por: Mao, Peiyao, et al.
Publicado: (2022)

Impact of ex vivo Sample Handling on DNA Methylation Profiles in Human Cord Blood and Neonatal Dried Blood Spots
por: Sasaki, Aya, et al.
Publicado: (2020)

The evolution of nanopore sequencing
por: Wang, Yue, et al.
Publicado: (2015)

The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model
por: Diamandas, Alexander, et al.
Publicado: (2021)

ARGem: a new metagenomics pipeline for antibiotic resistance genes: metadata, analysis, and visualization
por: Liang, Xiao, et al.
Publicado: (2023)

Clinical Performance Evaluation of VersaTrek 528 Blood Culture System in a Chinese Tertiary Hospital
por: Yue, Pinli, et al.
Publicado: (2018)

Development of novel parameters for pathogen identification in clinical metagenomic next-generation sequencing
por: Jiang, Xiwen, et al.
Publicado: (2023)

Origin Sample Prediction and Spatial Modeling of Antimicrobial Resistance in Metagenomic Sequencing Data
por: Zhelyazkova, Maya, et al.
Publicado: (2021)

High Prevalence of Extended-Spectrum Beta-Lactamases in Escherichia coli Strains Collected From Strictly Defined Community-Acquired Urinary Tract Infections in Adults in China: A Multicenter Prospective Clinical Microbiological and Molecular Study
por: Jia, Peiyao, et al.
Publicado: (2021)

Modification mapping by nanopore sequencing
por: White, Laura K., et al.
Publicado: (2022)

Nanopore adaptive sampling: a tool for enrichment of low abundance species in metagenomic samples
por: Martin, Samuel, et al.
Publicado: (2022)

Characterization and simulation of metagenomic nanopore sequencing data with Meta-NanoSim
por: Yang, Chen, et al.
Publicado: (2023)

Pangenome graphs in infectious disease: a comprehensive genetic variation analysis of Neisseria meningitidis leveraging Oxford Nanopore long reads
por: Yang, Zuyu, et al.
Publicado: (2023)

A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required
por: Dering, Carmen, et al.
Publicado: (2014)

Mobile antibiotic resistome in wastewater treatment plants revealed by Nanopore metagenomic sequencing
por: Che, You, et al.
Publicado: (2019)

Blood cell traits and risk of glaucoma: A two-sample mendelian randomization study
por: Song, De-Juan, et al.
Publicado: (2023)

Serotype Distribution, Antimicrobial Susceptibility, Multilocus Sequencing Type and Virulence of Invasive Streptococcus pneumoniae in China: A Six-Year Multicenter Study
por: Zhou, Menglan, et al.
Publicado: (2022)

The cellular roles of Ccr4-NOT in model and pathogenic fungi—implications for fungal virulence
por: Panepinto, John C., et al.
Publicado: (2013)

Shotgun-metagenomics based prediction of antibiotic resistance and virulence determinants in Staphylococcus aureus from periprosthetic tissue on blood culture bottles
por: Sanabria, Adriana Maria, et al.
Publicado: (2021)

Accurate Detection of HPV Integration Sites in Cervical Cancer Samples Using the Nanopore MinION Sequencer Without Error Correction
por: Yang, Wenjuan, et al.
Publicado: (2020)

Deep metagenomic sequencing for endophthalmitis pathogen detection using a nanopore platform
por: Low, Liying, et al.
Publicado: (2022)

Metagenomic Nanopore Sequencing of Influenza Virus Direct from Clinical Respiratory Samples
por: Lewandowski, Kuiama, et al.
Publicado: (2019)

Parallel DNA Extraction From Whole Blood for Rapid Sample Generation in Genetic Epidemiological Studies
por: Lee, Kiara, et al.
Publicado: (2020)

Rapid Detection of Bacterial Pathogens and Antimicrobial Resistance Genes in Clinical Urine Samples With Urinary Tract Infection by Metagenomic Nanopore Sequencing
por: Zhang, Lei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j21o4m185jhbn16ia0m2mhae39