Drug-induced cystitis caused by herbal medicine (Bofutsushosan)

Bofutsushosan (BTS), one of many traditional Japanese medicines (Kampo medicines) is attracting attention for obesity and metabolic syndrome. We report allergic cystitis caused by 8-year BTS usage in a 70-year-old female. The patient presented with micturition pain with sterile pyuria over a 3-month...

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Detalles Bibliográficos
Autores principales: Kato, Kumiko, Matsushita, Aika, Suzuki, Shoji, Sai, Hiroki, Hirabayashi, Hiroki, Hattori, Ryohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Inflammation and Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024595/
https://www.ncbi.nlm.nih.gov/pubmed/33850729
http://dx.doi.org/10.1016/j.eucr.2021.101644
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author Kato, Kumiko
Matsushita, Aika
Suzuki, Shoji
Sai, Hiroki
Hirabayashi, Hiroki
Hattori, Ryohei
author_facet Kato, Kumiko
Matsushita, Aika
Suzuki, Shoji
Sai, Hiroki
Hirabayashi, Hiroki
Hattori, Ryohei
author_sort Kato, Kumiko
collection PubMed
description Bofutsushosan (BTS), one of many traditional Japanese medicines (Kampo medicines) is attracting attention for obesity and metabolic syndrome. We report allergic cystitis caused by 8-year BTS usage in a 70-year-old female. The patient presented with micturition pain with sterile pyuria over a 3-month period. Cystoscopy showed diffuse urothelial erythema and edema. Urine cytology specimens showed increased eosinophilic cells. By discontinuing BTS, the cystitis symptoms disappeared after 4 days, and urinalysis normalized. Resuming BTS without physician approval resulted in cystitis symptoms and after cessation the symptoms rapidly subsided. This is the first English case report linking allergic cystitis to herbal medicine.
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spelling pubmed-80245952021-04-12 Drug-induced cystitis caused by herbal medicine (Bofutsushosan) Kato, Kumiko Matsushita, Aika Suzuki, Shoji Sai, Hiroki Hirabayashi, Hiroki Hattori, Ryohei Urol Case Rep Inflammation and Infection Bofutsushosan (BTS), one of many traditional Japanese medicines (Kampo medicines) is attracting attention for obesity and metabolic syndrome. We report allergic cystitis caused by 8-year BTS usage in a 70-year-old female. The patient presented with micturition pain with sterile pyuria over a 3-month period. Cystoscopy showed diffuse urothelial erythema and edema. Urine cytology specimens showed increased eosinophilic cells. By discontinuing BTS, the cystitis symptoms disappeared after 4 days, and urinalysis normalized. Resuming BTS without physician approval resulted in cystitis symptoms and after cessation the symptoms rapidly subsided. This is the first English case report linking allergic cystitis to herbal medicine. Elsevier 2021-03-19 /pmc/articles/PMC8024595/ /pubmed/33850729 http://dx.doi.org/10.1016/j.eucr.2021.101644 Text en © 2021 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Inflammation and Infection
Kato, Kumiko
Matsushita, Aika
Suzuki, Shoji
Sai, Hiroki
Hirabayashi, Hiroki
Hattori, Ryohei
Drug-induced cystitis caused by herbal medicine (Bofutsushosan)
title Drug-induced cystitis caused by herbal medicine (Bofutsushosan)
title_full Drug-induced cystitis caused by herbal medicine (Bofutsushosan)
title_fullStr Drug-induced cystitis caused by herbal medicine (Bofutsushosan)
title_full_unstemmed Drug-induced cystitis caused by herbal medicine (Bofutsushosan)
title_short Drug-induced cystitis caused by herbal medicine (Bofutsushosan)
title_sort drug-induced cystitis caused by herbal medicine (bofutsushosan)
topic Inflammation and Infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024595/
https://www.ncbi.nlm.nih.gov/pubmed/33850729
http://dx.doi.org/10.1016/j.eucr.2021.101644
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