Cargando…

3,3′-Diindolylmethane Promotes Gastric Cancer Progression via β-TrCP-Mediated NF-κB Activation in Gastric Cancer-Derived MSCs

Gastric cancer is a malignant tumor characterized by high morbidity and invasion. Surgery combined with chemo-radiotherapy is the most common treatment for gastric cancer, while multiple drug resistance always results in treatment failure. Once the anti-tumor drugs enter the tumor foci, tumor cells...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Hui, Sun, Yaoxiang, Ruan, Hongru, Ji, Cheng, Zhang, Jiahui, Wu, Peipei, Li, Linli, Huang, Chihan, Jia, Yuanwang, Zhang, Xu, Xu, Wenrong, Jiang, Jiajia, Qian, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024625/ https://www.ncbi.nlm.nih.gov/pubmed/33842314 http://dx.doi.org/10.3389/fonc.2021.603533

Ejemplares similares

Anti-cancer drug 3,3′-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis
por: Zhu, Yanhua, et al.
Publicado: (2016)

3,3′-Diindolylmethane stimulates exosomal Wnt11 autocrine signaling in human umbilical cord mesenchymal stem cells to enhance wound healing
por: Shi, Hui, et al.
Publicado: (2017)

3,3'-Diindolylmethane induces gastric cancer cells death via STIM1 mediated store-operated calcium entry
por: Ye, Yang, et al.
Publicado: (2021)

A selective aryl hydrocarbon receptor modulator 3,3'-Diindolylmethane inhibits gastric cancer cell growth
por: Yin, Xiao-Fei, et al.
Publicado: (2012)

Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction
por: Jaffry, Uzma, et al.
Publicado: (2023)

3,3′-Diindolylmethane: A Promising Sensitizer of γ-Irradiation
por: Wang, Wenjing, et al.
Publicado: (2015)

Cellular and Molecular Mechanisms of 3,3′-Diindolylmethane in Gastrointestinal Cancer
por: Kim, Soo Mi
Publicado: (2016)

3,3’-Diindolylmethane induces apoptosis and autophagy in fission yeast
por: Emami, Parvaneh, et al.
Publicado: (2021)

Structural basis of βTrCP1-associated GLI3 processing
por: Shafique, Shagufta, et al.
Publicado: (2019)

Interactions between β-Lactoglobulin and 3,3′-Diindolylmethane in Model System
por: Wang, Cuina, et al.
Publicado: (2019)

Amelioration of Hyperglycemia-Induced Nephropathy by 3,3′-Diindolylmethane in Diabetic Mice
por: Choi, Kyeong-Mi, et al.
Publicado: (2019)

Regulation of Interleukin-10 Receptor Ubiquitination and Stability by Beta-TrCP-Containing Ubiquitin E3 Ligase
por: Jiang, Hui, et al.
Publicado: (2011)

β-TrCP1 facilitates cell cycle checkpoint activation, DNA repair, and cell survival through ablation of β-TrCP2 in response to genotoxic stress
por: Islam, Sehbanul, et al.
Publicado: (2021)

Physicochemical and Microstructural Properties of Polymerized Whey Protein Encapsulated 3,3′-Diindolylmethane Nanoparticles
por: Khan, Abbas, et al.
Publicado: (2019)

3,3′-Diindolylmethane protects cardiomyocytes from LPS-induced inflammatory response and apoptosis
por: Luo, Qiang, et al.
Publicado: (2018)

Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells
por: Gao, Xiang, et al.
Publicado: (2020)

Indoles Derived From Glucobrassicin: Cancer Chemoprevention by Indole-3-Carbinol and 3,3'-Diindolylmethane
por: Williams, David E.
Publicado: (2021)

3,3′-Diindolylmethane Augments 5-Fluorouracil-InducedGrowth Suppression in Gastric Cancer Cells through Suppression of the Akt/GSK-3β and WNT/Beta-Catenin
por: Li, Cong Shan, et al.
Publicado: (2023)

NORE1A Regulates MDM2 Via β-TrCP
por: Schmidt, M. Lee, et al.
Publicado: (2016)

Targeting Bone Remodeling by Isoflavone and 3,3′-Diindolylmethane in the Context of Prostate Cancer Bone Metastasis
por: Li, Yiwei, et al.
Publicado: (2012)

Role of BioResponse 3,3′-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience
por: Li, Yiwei, et al.
Publicado: (2016)

Molecular Simulation Studies of 3,3′-Diindolylmethane as a Potent MicroRNA-21 Antagonist
por: Junaid, Md., et al.
Publicado: (2017)

3,3′-Diindolylmethane Enhances Fluorouracil Sensitivity via Inhibition of Pyrimidine Metabolism in Colorectal Cancer
por: Zhang, Jieping, et al.
Publicado: (2022)

HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation
por: Wu, Peipei, et al.
Publicado: (2021)

Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications
por: Jia, Yuanwang, et al.
Publicado: (2022)

3,3′-Diindolylmethane inhibits the invasion and metastasis of nasopharyngeal carcinoma cells in vitro and in vivo by regulation of epithelial mesenchymal transition
por: WU, TINGTING, et al.
Publicado: (2014)

Comparative preclinical pharmacokinetics study of 3,3′-diindolylmethane formulations: is personalized treatment and targeted chemoprevention in the horizon?
por: Paltsev, Mikhail, et al.
Publicado: (2013)

3,3′-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro
por: Xia, Zun-En, et al.
Publicado: (2018)

3,3′-Diindolylmethane (DIM): A Potential Therapeutic Agent against Cariogenic Streptococcus mutans Biofilm
por: Baruch, Yifat, et al.
Publicado: (2023)

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression
por: Seki, Akiko, et al.
Publicado: (2008)

Anticancer effects of 3,3′-diindolylmethane are associated with G1 arrest and mitochondria-dependent apoptosis in human nasopharyngeal carcinoma cells
por: XU, YU, et al.
Publicado: (2013)

Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP
por: Maluquer de Motes, Carlos, et al.
Publicado: (2017)

Identification of a novel YAP–14-3-3ζ negative feedback loop in gastric cancer
por: Zhang, Bin, et al.
Publicado: (2017)

Estrogen Induced Metastatic Modulators MMP-2 and MMP-9 Are Targets of 3,3′-Diindolylmethane in Thyroid Cancer
por: Rajoria, Shilpi, et al.
Publicado: (2011)

3,3′-Diindolylmethane Induces G(1) Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells
por: Shorey, Lyndsey E., et al.
Publicado: (2012)

Sulindac, 3,3’-diindolylmethane and curcumin reduce carcinogenesis in the Pirc rat, an Apc-driven model of colon carcinogenesis
por: Femia, Angelo Pietro, et al.
Publicado: (2015)

3,3′-Diindolylmethane enhances apoptosis in docetaxel-treated breast cancer cells by generation of reactive oxygen species
por: Lanza-Jacoby, Susan, et al.
Publicado: (2018)

The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans
por: Kim, Yong-Guy, et al.
Publicado: (2022)

Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3′-diindolylmethane through the mitochondrial pathway
por: Nachshon-Kedmi, M, et al.
Publicado: (2004)

β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling
por: Liu, Jin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_171ev0c77pa92fbpul14q6npne