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In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole

Using polymers as additives to formulate ternary amorphous solid dispersions (ASDs) has successfully been established to increase the bioavailability of poorly soluble drugs, when one polymer is not able to provide both, stabilizing the drug in the matrix and the supersaturated solution. Therefore,...

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Detalles Bibliográficos
Autores principales:	Bachmaier, Rafael D., Monschke, Marius, Faber, Thilo, Krome, Anna K., Pellequer, Yann, Stoyanov, Edmont, Lamprecht, Alf, Wagner, Karl G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024662/ https://www.ncbi.nlm.nih.gov/pubmed/33851133 http://dx.doi.org/10.1016/j.ijpx.2021.100076

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