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Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of nascent-chain disulfide bond formation

The mammalian endoplasmic reticulum (ER) harbors more than 20 members of the protein disulfide isomerase (PDI) family that act to maintain proteostasis. Herein, we developed an in vitro system for directly monitoring PDI- or ERp46-catalyzed disulfide bond formation in ribosome-associated nascent cha...

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Detalles Bibliográficos
Autores principales:	Hirayama, Chihiro, Machida, Kodai, Noi, Kentaro, Murakawa, Tadayoshi, Okumura, Masaki, Ogura, Teru, Imataka, Hiroaki, Inaba, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024706/ https://www.ncbi.nlm.nih.gov/pubmed/33855279 http://dx.doi.org/10.1016/j.isci.2021.102296

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