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A novel 3D polycaprolactone high-throughput system for evaluation of toxicity in normoxia and hypoxia
Two-dimensional (2D) culturing of cancer cells has been indispensable for the development of anti-cancer drugs. Drug development, however, is lengthy and costly with a high attrition rate, calling to mind that 2D culturing does not mimic the three-dimensional (3D) tumour microenvironment in vivo. Th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024882/ https://www.ncbi.nlm.nih.gov/pubmed/33854950 http://dx.doi.org/10.1016/j.toxrep.2021.03.015 |