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Pharmacokinetic and Pharmacodynamic Evaluation of Ravulizumab in Adults with Severe Coronavirus Disease 2019
INTRODUCTION: Terminal complement amplification is hypothesized to be a key contributor to the clinical manifestations of severe coronavirus disease 2019 (COVID-19). Ravulizumab, a humanized monoclonal antibody that binds with high affinity to complement protein C5 and inhibits terminal complement a...
Autores principales: | McEneny-King, Alanna C., Monteleone, Jonathan P. R., Kazani, Shamsah D., Ortiz, Stephan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024938/ https://www.ncbi.nlm.nih.gov/pubmed/33826106 http://dx.doi.org/10.1007/s40121-021-00425-7 |
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