Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy

A 59-year-old woman with small-cell lung carcinoma achieved tumor disappearance after cisplatin-based chemotherapy (CBC) and radiation treatment but subsequently experienced right hemiparesis and aphasia. Brain magnetic resonance imaging revealed a left middle cerebral artery territory acute infarct...

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Autores principales: Ochiai, Yukiko, Tsunogae, Marie, Ueda, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024955/
https://www.ncbi.nlm.nih.gov/pubmed/33087671
http://dx.doi.org/10.2169/internalmedicine.5761-20
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author Ochiai, Yukiko
Tsunogae, Marie
Ueda, Masayuki
author_facet Ochiai, Yukiko
Tsunogae, Marie
Ueda, Masayuki
author_sort Ochiai, Yukiko
collection PubMed
description A 59-year-old woman with small-cell lung carcinoma achieved tumor disappearance after cisplatin-based chemotherapy (CBC) and radiation treatment but subsequently experienced right hemiparesis and aphasia. Brain magnetic resonance imaging revealed a left middle cerebral artery territory acute infarction and left internal carotid artery occlusion. Ultrasonography revealed a mobile thrombus in the left common and internal carotid arteries, and contrast computed tomography revealed a mural thrombus in the ascending aorta. Based on these findings, embolic stroke due to aortic mural thrombus following CBC was diagnosed. Aortic mural thrombus is a rare complication of CBC but carries a risk of embolic stroke.
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spelling pubmed-80249552021-04-15 Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy Ochiai, Yukiko Tsunogae, Marie Ueda, Masayuki Intern Med Case Report A 59-year-old woman with small-cell lung carcinoma achieved tumor disappearance after cisplatin-based chemotherapy (CBC) and radiation treatment but subsequently experienced right hemiparesis and aphasia. Brain magnetic resonance imaging revealed a left middle cerebral artery territory acute infarction and left internal carotid artery occlusion. Ultrasonography revealed a mobile thrombus in the left common and internal carotid arteries, and contrast computed tomography revealed a mural thrombus in the ascending aorta. Based on these findings, embolic stroke due to aortic mural thrombus following CBC was diagnosed. Aortic mural thrombus is a rare complication of CBC but carries a risk of embolic stroke. The Japanese Society of Internal Medicine 2020-10-21 2021-03-15 /pmc/articles/PMC8024955/ /pubmed/33087671 http://dx.doi.org/10.2169/internalmedicine.5761-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ochiai, Yukiko
Tsunogae, Marie
Ueda, Masayuki
Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy
title Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy
title_full Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy
title_fullStr Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy
title_full_unstemmed Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy
title_short Embolic Stroke Due to a Mural Thrombus in the Ascending Aorta Following Cisplatin-based Chemotherapy
title_sort embolic stroke due to a mural thrombus in the ascending aorta following cisplatin-based chemotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024955/
https://www.ncbi.nlm.nih.gov/pubmed/33087671
http://dx.doi.org/10.2169/internalmedicine.5761-20
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AT tsunogaemarie embolicstrokeduetoamuralthrombusintheascendingaortafollowingcisplatinbasedchemotherapy
AT uedamasayuki embolicstrokeduetoamuralthrombusintheascendingaortafollowingcisplatinbasedchemotherapy

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