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DEAD‐box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3‐piRISC

The piRNA amplification pathway in Bombyx is operated by Ago3 and Siwi in their piRISC form. The DEAD‐box protein, Vasa, facilitates Ago3‐piRISC production by liberating cleaved RNAs from Siwi‐piRISC in an ATP hydrolysis‐dependent manner. However, the Vasa‐like factor facilitating Siwi‐piRISC produc...

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Detalles Bibliográficos
Autores principales: Murakami, Ryo, Sumiyoshi, Tetsutaro, Negishi, Lumi, Siomi, Mikiko C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025031/
https://www.ncbi.nlm.nih.gov/pubmed/33555135
http://dx.doi.org/10.15252/embr.202051313

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