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Research Note: An overview on distribution of fowl adenoviruses

Fowl adenoviruses (FAdV), detected during routine diagnostic investigations from 38 countries (5 continents) over a decade, were partially sequenced and grouped by phylogenetic analysis. The partial polymerase gene nucleotide sequences of the 365 fowl adenovirus isolates resulted in the following sp...

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Autores principales: Kiss, I., Homonnay, Z.G., Mató, T., Bányai, K., Palya, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025051/
https://www.ncbi.nlm.nih.gov/pubmed/33773159
http://dx.doi.org/10.1016/j.psj.2021.101052
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author Kiss, I.
Homonnay, Z.G.
Mató, T.
Bányai, K.
Palya, V.
author_facet Kiss, I.
Homonnay, Z.G.
Mató, T.
Bányai, K.
Palya, V.
author_sort Kiss, I.
collection PubMed
description Fowl adenoviruses (FAdV), detected during routine diagnostic investigations from 38 countries (5 continents) over a decade, were partially sequenced and grouped by phylogenetic analysis. The partial polymerase gene nucleotide sequences of the 365 fowl adenovirus isolates resulted in the following species distribution: 11% FAdV-A; 3% FAdV-B; 2% FAdV-C; 34% FAdV-D; and 50% FAdV-E. Noticeably, only 79 of the detected strains could be associated with adenovirus-specific pathologic conditions: 62 (79%) with inclusion body hepatitis; 9 (11%) with gizzard erosion; and 8 (10%) with hepatitis hydropericardium syndrome. The remainder of the FAdV strains was detected as concomitant infection from other disease conditions almost exclusively in boilers of 27 to 42 d of age: the majority of them was FAdV-E followed by FAdV-D, and to a lesser extent of FAdV-A, B, and C, the latter ones have not been associated with any of the established adenovirus-caused syndromes in our collection. The highest ratio of coinfections was observed for FAdV-B (62%), while it was about 30% for the rest of the FAdV species. The most frequent coinfection, in connection with all FAdV species, was with the avian infectious bronchitis virus. The presented database will serve as the basis for comparative whole genome and cross-neutralization analysis of selected FAdV isolates.
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spelling pubmed-80250512021-04-13 Research Note: An overview on distribution of fowl adenoviruses Kiss, I. Homonnay, Z.G. Mató, T. Bányai, K. Palya, V. Poult Sci IMMUNOLOGY, HEALTH AND DISEASE Fowl adenoviruses (FAdV), detected during routine diagnostic investigations from 38 countries (5 continents) over a decade, were partially sequenced and grouped by phylogenetic analysis. The partial polymerase gene nucleotide sequences of the 365 fowl adenovirus isolates resulted in the following species distribution: 11% FAdV-A; 3% FAdV-B; 2% FAdV-C; 34% FAdV-D; and 50% FAdV-E. Noticeably, only 79 of the detected strains could be associated with adenovirus-specific pathologic conditions: 62 (79%) with inclusion body hepatitis; 9 (11%) with gizzard erosion; and 8 (10%) with hepatitis hydropericardium syndrome. The remainder of the FAdV strains was detected as concomitant infection from other disease conditions almost exclusively in boilers of 27 to 42 d of age: the majority of them was FAdV-E followed by FAdV-D, and to a lesser extent of FAdV-A, B, and C, the latter ones have not been associated with any of the established adenovirus-caused syndromes in our collection. The highest ratio of coinfections was observed for FAdV-B (62%), while it was about 30% for the rest of the FAdV species. The most frequent coinfection, in connection with all FAdV species, was with the avian infectious bronchitis virus. The presented database will serve as the basis for comparative whole genome and cross-neutralization analysis of selected FAdV isolates. Elsevier 2021-02-16 /pmc/articles/PMC8025051/ /pubmed/33773159 http://dx.doi.org/10.1016/j.psj.2021.101052 Text en © 2021 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle IMMUNOLOGY, HEALTH AND DISEASE
Kiss, I.
Homonnay, Z.G.
Mató, T.
Bányai, K.
Palya, V.
Research Note: An overview on distribution of fowl adenoviruses
title Research Note: An overview on distribution of fowl adenoviruses
title_full Research Note: An overview on distribution of fowl adenoviruses
title_fullStr Research Note: An overview on distribution of fowl adenoviruses
title_full_unstemmed Research Note: An overview on distribution of fowl adenoviruses
title_short Research Note: An overview on distribution of fowl adenoviruses
title_sort research note: an overview on distribution of fowl adenoviruses
topic IMMUNOLOGY, HEALTH AND DISEASE
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025051/
https://www.ncbi.nlm.nih.gov/pubmed/33773159
http://dx.doi.org/10.1016/j.psj.2021.101052
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