Discovery of rare sulfated N-unsubstituted glucosamine based heparan sulfate analogs selectively activating chemokines

Achieving selective inhibition of chemokines with structurally well-defined heparan sulfate (HS) oligosaccharides can provide important insights into cancer cell migration and metastasis. However, HS is highly heterogeneous in chemical composition, which limits its therapeutic use. Here, we report t...

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Detalles Bibliográficos
Autores principales: Jain, Prashant, Shanthamurthy, Chethan D., Leviatan Ben-Arye, Shani, Woods, Robert J., Kikkeri, Raghavendra, Padler-Karavani, Vered
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025211/
https://www.ncbi.nlm.nih.gov/pubmed/33889380
http://dx.doi.org/10.1039/d0sc05862a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025211/
https://www.ncbi.nlm.nih.gov/pubmed/33889380
http://dx.doi.org/10.1039/d0sc05862a

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