miR-146 connects stem cell identity with metabolism and pharmacological resistance in breast cancer

Although ectopic overexpression of miRNAs can influence mammary normal and cancer stem cells (SCs/CSCs), their physiological relevance remains uncertain. Here, we show that miR-146 is relevant for SC/CSC activity. MiR-146a/b expression is high in SCs/CSCs from human/mouse primary mammary tissues, co...

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Detalles Bibliográficos
Autores principales: Tordonato, Chiara, Marzi, Matteo Jacopo, Giangreco, Giovanni, Freddi, Stefano, Bonetti, Paola, Tosoni, Daniela, Di Fiore, Pier Paolo, Nicassio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025236/
https://www.ncbi.nlm.nih.gov/pubmed/33819341
http://dx.doi.org/10.1083/jcb.202009053

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