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Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer

Triple-negative breast cancers (TNBCs) are associated with poor survival mediated by treatment resistance. TNBCs are fibrotic, yet little is known regarding how the extracellular matrix (ECM) evolves following therapy and whether it impacts treatment response. Analysis revealed that while primary un...

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Detalles Bibliográficos
Autores principales: Drain, Allison P., Zahir, Nastaran, Northey, Jason J., Zhang, Hui, Huang, Po-Jui, Maller, Ori, Lakins, Johnathon N., Yu, Xinmiao, Leight, Jennifer L., Alston-Mills, Brenda P., Hwang, E. Shelley, Chen, Yunn-Yi, Park, Catherine C., Weaver, Valerie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025243/
https://www.ncbi.nlm.nih.gov/pubmed/33822843
http://dx.doi.org/10.1084/jem.20191360

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