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Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer
Triple-negative breast cancers (TNBCs) are associated with poor survival mediated by treatment resistance. TNBCs are fibrotic, yet little is known regarding how the extracellular matrix (ECM) evolves following therapy and whether it impacts treatment response. Analysis revealed that while primary un...
Autores principales: | Drain, Allison P., Zahir, Nastaran, Northey, Jason J., Zhang, Hui, Huang, Po-Jui, Maller, Ori, Lakins, Johnathon N., Yu, Xinmiao, Leight, Jennifer L., Alston-Mills, Brenda P., Hwang, E. Shelley, Chen, Yunn-Yi, Park, Catherine C., Weaver, Valerie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025243/ https://www.ncbi.nlm.nih.gov/pubmed/33822843 http://dx.doi.org/10.1084/jem.20191360 |
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