Regnase-1 is essential for B cell homeostasis to prevent immunopathology

Regnase-1 is an emerging regulator of immune responses with essential roles in the posttranscriptional control of immune cell activation. Regnase-1 is expressed in B cells; however, its B cell–specific functions remain unknown. Here, we demonstrate that Regnase-1 prevents severe autoimmune pathology...

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Detalles Bibliográficos
Autores principales: Bhat, Numana, Virgen-Slane, Richard, Ramezani-Rad, Parham, Leung, Charlotte R., Chen, Cindi, Balsells, Daniel, Shukla, Ashima, Kao, Elaine, Apgar, John R., Fu, Mingui, Ware, Carl F., Rickert, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025244/
https://www.ncbi.nlm.nih.gov/pubmed/33822844
http://dx.doi.org/10.1084/jem.20200971

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