The dark side of histones: genomic organization and role of oncohistones in cancer

BACKGROUND: The oncogenic role of histone mutations is one of the most relevant discovery in cancer epigenetics. Recurrent mutations targeting histone genes have been described in pediatric brain tumors, chondroblastoma, giant cell tumor of bone and other tumor types. The demonstration that mutant h...

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Detalles Bibliográficos
Autores principales: Amatori, Stefano, Tavolaro, Simona, Gambardella, Stefano, Fanelli, Mirco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025322/
https://www.ncbi.nlm.nih.gov/pubmed/33827674
http://dx.doi.org/10.1186/s13148-021-01057-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025322/
https://www.ncbi.nlm.nih.gov/pubmed/33827674
http://dx.doi.org/10.1186/s13148-021-01057-x

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