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The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice

BACKGROUND: C–C chemokine receptor 2 (CCR2) signaling plays a key role in pain associated with experimental murine osteoarthritis (OA) after destabilization of the medial meniscus (DMM). Here, we aimed to assess if CCR2 expressed by intra-articular sensory neurons contributes to knee hyperalgesia in...

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Detalles Bibliográficos
Autores principales:	Ishihara, Shingo, Obeidat, Alia M., Wokosin, David L., Ren, Dongjun, Miller, Richard J., Malfait, Anne-Marie, Miller, Rachel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025346/ https://www.ncbi.nlm.nih.gov/pubmed/33827672 http://dx.doi.org/10.1186/s13075-021-02486-y

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