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Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina
BACKGROUND: Adult mesenchymal stem cells (MSCs) have been studied extensively for regenerative medicine; however, they have limited proliferation in vitro, and the long culture time induces cell senescence. MSCs also contribute to tissue repair through their paracrine function. In this study, we sou...
Autores principales: | Zhuang, Guobing, Wen, Yan, Briggs, Mason, Shao, Qingchun, Tran, Darlene, Wang, Hongbo, Chen, Bertha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025391/ https://www.ncbi.nlm.nih.gov/pubmed/33823931 http://dx.doi.org/10.1186/s13287-021-02292-y |
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