Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs

The preparation of modified Mohs paste, commonly used for malignant wounds, requires time and effort. Moreover, metal-containing liquid waste is generated when malignant wounds are scrubbed. Therefore, we previously changed the base material of the modified Mohs paste from zinc oxide starch powder t...

Descripción completa

Detalles Bibliográficos
Autores principales: FUKUYAMA, Yasuhiro, MARUO, Takuya, NISHIYAMA, Yuta, NEMOTO, Yuki, MURAYAMA, Kaho, KAYANUMA, Hideki, KAWARAI, Shinpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025422/
https://www.ncbi.nlm.nih.gov/pubmed/33441500
http://dx.doi.org/10.1292/jvms.20-0670
_version_ 1783675490865774592
author FUKUYAMA, Yasuhiro
MARUO, Takuya
NISHIYAMA, Yuta
NEMOTO, Yuki
MURAYAMA, Kaho
KAYANUMA, Hideki
KAWARAI, Shinpei
author_facet FUKUYAMA, Yasuhiro
MARUO, Takuya
NISHIYAMA, Yuta
NEMOTO, Yuki
MURAYAMA, Kaho
KAYANUMA, Hideki
KAWARAI, Shinpei
author_sort FUKUYAMA, Yasuhiro
collection PubMed
description The preparation of modified Mohs paste, commonly used for malignant wounds, requires time and effort. Moreover, metal-containing liquid waste is generated when malignant wounds are scrubbed. Therefore, we previously changed the base material of the modified Mohs paste from zinc oxide starch powder to carboxymethyl cellulose (CMC). The novel modified Mohs paste based on CMC (moM-CMC sol) may reduce these disadvantages. In the present study, the moM-CMC sol was applied to malignant tumors in three dogs to manage bleeding and malodor. The moM-CMC sol transitioned into a gel on the tumors within an hour of application and could be easily removed. The symptoms resolved in all cases. The moM-CMC sol could be beneficial for dogs with malignant wounds.
format Online
Article
Text
id pubmed-8025422
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Japanese Society of Veterinary Science
record_format MEDLINE/PubMed
spelling pubmed-80254222021-04-13 Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs FUKUYAMA, Yasuhiro MARUO, Takuya NISHIYAMA, Yuta NEMOTO, Yuki MURAYAMA, Kaho KAYANUMA, Hideki KAWARAI, Shinpei J Vet Med Sci Internal Medicine The preparation of modified Mohs paste, commonly used for malignant wounds, requires time and effort. Moreover, metal-containing liquid waste is generated when malignant wounds are scrubbed. Therefore, we previously changed the base material of the modified Mohs paste from zinc oxide starch powder to carboxymethyl cellulose (CMC). The novel modified Mohs paste based on CMC (moM-CMC sol) may reduce these disadvantages. In the present study, the moM-CMC sol was applied to malignant tumors in three dogs to manage bleeding and malodor. The moM-CMC sol transitioned into a gel on the tumors within an hour of application and could be easily removed. The symptoms resolved in all cases. The moM-CMC sol could be beneficial for dogs with malignant wounds. The Japanese Society of Veterinary Science 2021-01-13 2021-03 /pmc/articles/PMC8025422/ /pubmed/33441500 http://dx.doi.org/10.1292/jvms.20-0670 Text en ©2021 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
FUKUYAMA, Yasuhiro
MARUO, Takuya
NISHIYAMA, Yuta
NEMOTO, Yuki
MURAYAMA, Kaho
KAYANUMA, Hideki
KAWARAI, Shinpei
Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs
title Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs
title_full Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs
title_fullStr Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs
title_full_unstemmed Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs
title_short Application of a novel carboxymethyl cellulose-based Mohs sol–gel on malignant wounds in three dogs
title_sort application of a novel carboxymethyl cellulose-based mohs sol–gel on malignant wounds in three dogs
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025422/
https://www.ncbi.nlm.nih.gov/pubmed/33441500
http://dx.doi.org/10.1292/jvms.20-0670
work_keys_str_mv AT fukuyamayasuhiro applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs
AT maruotakuya applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs
AT nishiyamayuta applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs
AT nemotoyuki applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs
AT murayamakaho applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs
AT kayanumahideki applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs
AT kawaraishinpei applicationofanovelcarboxymethylcellulosebasedmohssolgelonmalignantwoundsinthreedogs

Ejemplares similares