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Phgdh serves a protective role in Il-1β induced chondrocyte inflammation and oxidative-stress damage

The primary pathological changes observed in osteoarthritis (OA) involve inflammation and degeneration of chondrocytes. 3-phosphoglycerate dehydrogenase (Phgdh), a rate-limiting enzyme involved in the conversion of 3-phosphoglycerate to serine, serves as a crucial molecular component of cell growth...

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Detalles Bibliográficos
Autores principales:	Huang, Hefei, Liu, Keting, Ou, Hua, Qian, Xuankun, Wan, Jianshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025466/ https://www.ncbi.nlm.nih.gov/pubmed/33846783 http://dx.doi.org/10.3892/mmr.2021.12058

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