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Prevalence and clinical phenotype of the triplicated α-globin genes and its ethnic and geographical distribution in Guizhou of China

BACKGROUND: α-thalassemia is relatively endemic in Guizhou province of southwestern China. To predict the clinical manifestations of α-globin gene aberration for genetic counseling, we examined the prevalence of the α-globin triplication and the genotype–phenotype correlation in this subpopulation M...

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Detalles Bibliográficos
Autores principales:	Luo, Xi, Zhang, Xiang-mei, Wu, Liu-song, Chen, Jindong, Chen, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025570/ https://www.ncbi.nlm.nih.gov/pubmed/33827577 http://dx.doi.org/10.1186/s12920-021-00944-9

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