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K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases

Infectious disease is a great enemy of humankind. The ravages of COVID-19 are leading to profound crises across the world. There is an urgent requirement for analyzing the current pandemic situation, predicting trends over time, and assessing the effectiveness of containment measures. Thus, numerous...

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Detalles Bibliográficos
Autores principales: Wang, Hongzhi, Miao, Zhiying, Zhang, Chaobao, Wei, Xiaona, Li, Xiangqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025586/
https://www.ncbi.nlm.nih.gov/pubmed/33841752
http://dx.doi.org/10.1016/j.csbj.2021.04.004
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author Wang, Hongzhi
Miao, Zhiying
Zhang, Chaobao
Wei, Xiaona
Li, Xiangqi
author_facet Wang, Hongzhi
Miao, Zhiying
Zhang, Chaobao
Wei, Xiaona
Li, Xiangqi
author_sort Wang, Hongzhi
collection PubMed
description Infectious disease is a great enemy of humankind. The ravages of COVID-19 are leading to profound crises across the world. There is an urgent requirement for analyzing the current pandemic situation, predicting trends over time, and assessing the effectiveness of containment measures. Thus, numerous statistical models, primarily based on the susceptible–exposed–infected–recovered or removed (SEIR) model, have been established. However, these models are highly technical, which are difficult for the public and governing bodies to understand and use. To address this issue, we developed a simple operating software based on our improved K-SEIR model termed as the kernelkernel SEIR simulator (K-SEIR-Sim). This software includes natural propagation parameters, containment measure parameters, and certain characteristic parameters that can deduce the effects of natural propagation and containment measures. Further, the applicability of the proposed software was demonstrated using the example of the COVID-19 outbreak in the United States and the city of Wuhan, China. Operating results verified the potency of the proposed software in evaluating the epidemic situation and human intervention during COVID-19. Importantly, the software can perform real-time, backward-looking, and forward-looking analysis by functioning in data-driven and model-driven ways. All of them have considerable practical values in their applications according to the actual needs of personal use. Conclusively, K-SEIR-Sim is the first simple customized operating software that is highly valuable for the global fight against COVID-19 and other infectious diseases.
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spelling pubmed-80255862021-04-07 K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases Wang, Hongzhi Miao, Zhiying Zhang, Chaobao Wei, Xiaona Li, Xiangqi Comput Struct Biotechnol J Research Article Infectious disease is a great enemy of humankind. The ravages of COVID-19 are leading to profound crises across the world. There is an urgent requirement for analyzing the current pandemic situation, predicting trends over time, and assessing the effectiveness of containment measures. Thus, numerous statistical models, primarily based on the susceptible–exposed–infected–recovered or removed (SEIR) model, have been established. However, these models are highly technical, which are difficult for the public and governing bodies to understand and use. To address this issue, we developed a simple operating software based on our improved K-SEIR model termed as the kernelkernel SEIR simulator (K-SEIR-Sim). This software includes natural propagation parameters, containment measure parameters, and certain characteristic parameters that can deduce the effects of natural propagation and containment measures. Further, the applicability of the proposed software was demonstrated using the example of the COVID-19 outbreak in the United States and the city of Wuhan, China. Operating results verified the potency of the proposed software in evaluating the epidemic situation and human intervention during COVID-19. Importantly, the software can perform real-time, backward-looking, and forward-looking analysis by functioning in data-driven and model-driven ways. All of them have considerable practical values in their applications according to the actual needs of personal use. Conclusively, K-SEIR-Sim is the first simple customized operating software that is highly valuable for the global fight against COVID-19 and other infectious diseases. Research Network of Computational and Structural Biotechnology 2021-04-07 /pmc/articles/PMC8025586/ /pubmed/33841752 http://dx.doi.org/10.1016/j.csbj.2021.04.004 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Wang, Hongzhi
Miao, Zhiying
Zhang, Chaobao
Wei, Xiaona
Li, Xiangqi
K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases
title K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases
title_full K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases
title_fullStr K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases
title_full_unstemmed K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases
title_short K-SEIR-Sim: A simple customized software for simulating the spread of infectious diseases
title_sort k-seir-sim: a simple customized software for simulating the spread of infectious diseases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025586/
https://www.ncbi.nlm.nih.gov/pubmed/33841752
http://dx.doi.org/10.1016/j.csbj.2021.04.004
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