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Regulation of temozolomide resistance in glioma cells via the RIP2/NF‐κB/MGMT pathway

BACKGROUND: Temozolomide (TMZ) is a first‐line chemotherapy drug for the treatment of malignant glioma and resistance to it poses a major challenge. Receptor‐interacting protein 2 (RIP2) is associated with the malignant character of cancer cells. However, it remains unclear whether RIP2 is involved...

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Detalles Bibliográficos
Autores principales: Hu, Yu‐Hua, Jiao, Bao‐Hua, Wang, Cheng‐Ye, Wu, Jian‐Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025621/
https://www.ncbi.nlm.nih.gov/pubmed/33460245
http://dx.doi.org/10.1111/cns.13591