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Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy

Cervical stump cancer, which arises in the remaining uterine cervix of a woman with a history of supravaginal hysterectomy, accounts for 1.6-4.4% of all cervical cancers. The close proximity of the rectosigmoid colon to the primary tumor, which is due to the absence of the uterine corpus, should be...

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Autores principales: Okada, Kohei, Oike, Takahiro, Ando, Ken, Kubo, Nobuteru, Ohno, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025798/
https://www.ncbi.nlm.nih.gov/pubmed/33842163
http://dx.doi.org/10.7759/cureus.13789
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author Okada, Kohei
Oike, Takahiro
Ando, Ken
Kubo, Nobuteru
Ohno, Tatsuya
author_facet Okada, Kohei
Oike, Takahiro
Ando, Ken
Kubo, Nobuteru
Ohno, Tatsuya
author_sort Okada, Kohei
collection PubMed
description Cervical stump cancer, which arises in the remaining uterine cervix of a woman with a history of supravaginal hysterectomy, accounts for 1.6-4.4% of all cervical cancers. The close proximity of the rectosigmoid colon to the primary tumor, which is due to the absence of the uterine corpus, should be considered carefully in the treatment planning of brachytherapy. Although three-dimensional image-guided brachytherapy (3D-IGBT) is used widely to treat cervical cancer in those with an intact uterine corpus, the safety and efficacy of 3D-IGBT for cervical stump cancer remains unclear. Here, we report a case of cervical stump cancer (T3bN1M0) treated successfully with definitive radiotherapy, which combined external beam radiotherapy and computed tomography (CT)-based IGBT. By applying the dose prescription concept used for definitive brachytherapy of cervical cancer with an intact uterine corpus, IGBT achieved satisfactory dose conformity to the tumor while sparing the adjacent rectosigmoid colon. This led to local tumor control for three years and eight months, with no late adverse effects. This case suggests that radiotherapy using CT-based IGBT is a safe and effective treatment for cervical stump cancer.
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spelling pubmed-80257982021-04-09 Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy Okada, Kohei Oike, Takahiro Ando, Ken Kubo, Nobuteru Ohno, Tatsuya Cureus Oncology Cervical stump cancer, which arises in the remaining uterine cervix of a woman with a history of supravaginal hysterectomy, accounts for 1.6-4.4% of all cervical cancers. The close proximity of the rectosigmoid colon to the primary tumor, which is due to the absence of the uterine corpus, should be considered carefully in the treatment planning of brachytherapy. Although three-dimensional image-guided brachytherapy (3D-IGBT) is used widely to treat cervical cancer in those with an intact uterine corpus, the safety and efficacy of 3D-IGBT for cervical stump cancer remains unclear. Here, we report a case of cervical stump cancer (T3bN1M0) treated successfully with definitive radiotherapy, which combined external beam radiotherapy and computed tomography (CT)-based IGBT. By applying the dose prescription concept used for definitive brachytherapy of cervical cancer with an intact uterine corpus, IGBT achieved satisfactory dose conformity to the tumor while sparing the adjacent rectosigmoid colon. This led to local tumor control for three years and eight months, with no late adverse effects. This case suggests that radiotherapy using CT-based IGBT is a safe and effective treatment for cervical stump cancer. Cureus 2021-03-09 /pmc/articles/PMC8025798/ /pubmed/33842163 http://dx.doi.org/10.7759/cureus.13789 Text en Copyright © 2021, Okada et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Okada, Kohei
Oike, Takahiro
Ando, Ken
Kubo, Nobuteru
Ohno, Tatsuya
Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
title Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
title_full Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
title_fullStr Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
title_full_unstemmed Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
title_short Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
title_sort cervical stump cancer treated with radiotherapy using computed tomography-guided brachytherapy
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025798/
https://www.ncbi.nlm.nih.gov/pubmed/33842163
http://dx.doi.org/10.7759/cureus.13789
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