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Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy
Cervical stump cancer, which arises in the remaining uterine cervix of a woman with a history of supravaginal hysterectomy, accounts for 1.6-4.4% of all cervical cancers. The close proximity of the rectosigmoid colon to the primary tumor, which is due to the absence of the uterine corpus, should be...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025798/ https://www.ncbi.nlm.nih.gov/pubmed/33842163 http://dx.doi.org/10.7759/cureus.13789 |
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author | Okada, Kohei Oike, Takahiro Ando, Ken Kubo, Nobuteru Ohno, Tatsuya |
author_facet | Okada, Kohei Oike, Takahiro Ando, Ken Kubo, Nobuteru Ohno, Tatsuya |
author_sort | Okada, Kohei |
collection | PubMed |
description | Cervical stump cancer, which arises in the remaining uterine cervix of a woman with a history of supravaginal hysterectomy, accounts for 1.6-4.4% of all cervical cancers. The close proximity of the rectosigmoid colon to the primary tumor, which is due to the absence of the uterine corpus, should be considered carefully in the treatment planning of brachytherapy. Although three-dimensional image-guided brachytherapy (3D-IGBT) is used widely to treat cervical cancer in those with an intact uterine corpus, the safety and efficacy of 3D-IGBT for cervical stump cancer remains unclear. Here, we report a case of cervical stump cancer (T3bN1M0) treated successfully with definitive radiotherapy, which combined external beam radiotherapy and computed tomography (CT)-based IGBT. By applying the dose prescription concept used for definitive brachytherapy of cervical cancer with an intact uterine corpus, IGBT achieved satisfactory dose conformity to the tumor while sparing the adjacent rectosigmoid colon. This led to local tumor control for three years and eight months, with no late adverse effects. This case suggests that radiotherapy using CT-based IGBT is a safe and effective treatment for cervical stump cancer. |
format | Online Article Text |
id | pubmed-8025798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-80257982021-04-09 Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy Okada, Kohei Oike, Takahiro Ando, Ken Kubo, Nobuteru Ohno, Tatsuya Cureus Oncology Cervical stump cancer, which arises in the remaining uterine cervix of a woman with a history of supravaginal hysterectomy, accounts for 1.6-4.4% of all cervical cancers. The close proximity of the rectosigmoid colon to the primary tumor, which is due to the absence of the uterine corpus, should be considered carefully in the treatment planning of brachytherapy. Although three-dimensional image-guided brachytherapy (3D-IGBT) is used widely to treat cervical cancer in those with an intact uterine corpus, the safety and efficacy of 3D-IGBT for cervical stump cancer remains unclear. Here, we report a case of cervical stump cancer (T3bN1M0) treated successfully with definitive radiotherapy, which combined external beam radiotherapy and computed tomography (CT)-based IGBT. By applying the dose prescription concept used for definitive brachytherapy of cervical cancer with an intact uterine corpus, IGBT achieved satisfactory dose conformity to the tumor while sparing the adjacent rectosigmoid colon. This led to local tumor control for three years and eight months, with no late adverse effects. This case suggests that radiotherapy using CT-based IGBT is a safe and effective treatment for cervical stump cancer. Cureus 2021-03-09 /pmc/articles/PMC8025798/ /pubmed/33842163 http://dx.doi.org/10.7759/cureus.13789 Text en Copyright © 2021, Okada et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Oncology Okada, Kohei Oike, Takahiro Ando, Ken Kubo, Nobuteru Ohno, Tatsuya Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy |
title | Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy |
title_full | Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy |
title_fullStr | Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy |
title_full_unstemmed | Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy |
title_short | Cervical Stump Cancer Treated With Radiotherapy Using Computed Tomography-Guided Brachytherapy |
title_sort | cervical stump cancer treated with radiotherapy using computed tomography-guided brachytherapy |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025798/ https://www.ncbi.nlm.nih.gov/pubmed/33842163 http://dx.doi.org/10.7759/cureus.13789 |
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