Deconvolution of intergenic polymorphisms determining high expression of Factor H binding protein in meningococcus and their association with invasive disease

Neisseria meningitidis is a strictly human pathogen and is the major cause of septicemia and meningitis worldwide. Factor H binding protein (fHbp) is a meningococcal surface-exposed lipoprotein that binds the human Complement factor H allowing the bacterium to evade the host innate immune response....

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Detalles Bibliográficos
Autores principales: Spinsanti, Marco, Brignoli, Tarcisio, Bodini, Margherita, Fontana, Lucia Eleonora, De Chiara, Matteo, Biolchi, Alessia, Muzzi, Alessandro, Scarlato, Vincenzo, Delany, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026042/
https://www.ncbi.nlm.nih.gov/pubmed/33770146
http://dx.doi.org/10.1371/journal.ppat.1009461

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