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Quantifying evolutionary importance of protein sites: A Tale of two measures
A key challenge in evolutionary biology is the accurate quantification of selective pressure on proteins and other biological macromolecules at single-site resolution. The evolutionary importance of a protein site under purifying selection is typically measured by the degree of conservation of the p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026052/ https://www.ncbi.nlm.nih.gov/pubmed/33826605 http://dx.doi.org/10.1371/journal.pgen.1009476 |