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Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
BACKGROUND: Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race/ethnicity. The purpose of this...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026066/ https://www.ncbi.nlm.nih.gov/pubmed/33826671 http://dx.doi.org/10.1371/journal.pone.0249188 |
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author | Monestime, Shanada Beech, Bettina Kermah, Dulcie Norris, Keith |
author_facet | Monestime, Shanada Beech, Bettina Kermah, Dulcie Norris, Keith |
author_sort | Monestime, Shanada |
collection | PubMed |
description | BACKGROUND: Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race/ethnicity. The purpose of this study was to compare the prevalence and predictors of ORCs by race/ethnicity among adults (>18) with MetS. METHODS: This was a retrospective, cross-sectional study using data from the 1999–2014 National Health and Nutrition Examination Survey (NHANES). A chi-square test was performed to determine differences in ORC prevalence between non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic participants with MetS. A multivariate logistic regression was used to evaluate predictors (race, sex, income, insurance, education, marital status, and smoking status) of ORC among adults with MetS. RESULTS: Of the 1,554 adults, the prevalence of ORC was 30.6% among NHWs, 51.3% in NHBs, and 54.1% in Hispanics (p = <0.001). Females were 6.27 times more likely to have an ORC compared to males (95% CI = 4.95–14.11). Compared to NHWs, NHBs were 2.1 times more likely to have an ORC (95% CI = 1.40–3.38); and Hispanics were 2.5 times more likely (95% CI = 1.39–4.77). For every 1-year unit increase in age, the odds of ORC increased by 3% (95% CI = 1.00–1.05). CONCLUSIONS: Among NHANES participants with MetS, the prevalence of ORCs was significantly higher in NHBs and Hispanics, females, and older adults with MetS. Future studies, by race/ethnicity, are warranted on mortality risk of persons with MetS and ORC. |
format | Online Article Text |
id | pubmed-8026066 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-80260662021-04-15 Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome Monestime, Shanada Beech, Bettina Kermah, Dulcie Norris, Keith PLoS One Research Article BACKGROUND: Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race/ethnicity. The purpose of this study was to compare the prevalence and predictors of ORCs by race/ethnicity among adults (>18) with MetS. METHODS: This was a retrospective, cross-sectional study using data from the 1999–2014 National Health and Nutrition Examination Survey (NHANES). A chi-square test was performed to determine differences in ORC prevalence between non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic participants with MetS. A multivariate logistic regression was used to evaluate predictors (race, sex, income, insurance, education, marital status, and smoking status) of ORC among adults with MetS. RESULTS: Of the 1,554 adults, the prevalence of ORC was 30.6% among NHWs, 51.3% in NHBs, and 54.1% in Hispanics (p = <0.001). Females were 6.27 times more likely to have an ORC compared to males (95% CI = 4.95–14.11). Compared to NHWs, NHBs were 2.1 times more likely to have an ORC (95% CI = 1.40–3.38); and Hispanics were 2.5 times more likely (95% CI = 1.39–4.77). For every 1-year unit increase in age, the odds of ORC increased by 3% (95% CI = 1.00–1.05). CONCLUSIONS: Among NHANES participants with MetS, the prevalence of ORCs was significantly higher in NHBs and Hispanics, females, and older adults with MetS. Future studies, by race/ethnicity, are warranted on mortality risk of persons with MetS and ORC. Public Library of Science 2021-04-07 /pmc/articles/PMC8026066/ /pubmed/33826671 http://dx.doi.org/10.1371/journal.pone.0249188 Text en © 2021 Monestime et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Monestime, Shanada Beech, Bettina Kermah, Dulcie Norris, Keith Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
title | Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
title_full | Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
title_fullStr | Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
title_full_unstemmed | Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
title_short | Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
title_sort | prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026066/ https://www.ncbi.nlm.nih.gov/pubmed/33826671 http://dx.doi.org/10.1371/journal.pone.0249188 |
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