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Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome

BACKGROUND: Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race/ethnicity. The purpose of this...

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Autores principales: Monestime, Shanada, Beech, Bettina, Kermah, Dulcie, Norris, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026066/
https://www.ncbi.nlm.nih.gov/pubmed/33826671
http://dx.doi.org/10.1371/journal.pone.0249188
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author Monestime, Shanada
Beech, Bettina
Kermah, Dulcie
Norris, Keith
author_facet Monestime, Shanada
Beech, Bettina
Kermah, Dulcie
Norris, Keith
author_sort Monestime, Shanada
collection PubMed
description BACKGROUND: Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race/ethnicity. The purpose of this study was to compare the prevalence and predictors of ORCs by race/ethnicity among adults (>18) with MetS. METHODS: This was a retrospective, cross-sectional study using data from the 1999–2014 National Health and Nutrition Examination Survey (NHANES). A chi-square test was performed to determine differences in ORC prevalence between non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic participants with MetS. A multivariate logistic regression was used to evaluate predictors (race, sex, income, insurance, education, marital status, and smoking status) of ORC among adults with MetS. RESULTS: Of the 1,554 adults, the prevalence of ORC was 30.6% among NHWs, 51.3% in NHBs, and 54.1% in Hispanics (p = <0.001). Females were 6.27 times more likely to have an ORC compared to males (95% CI = 4.95–14.11). Compared to NHWs, NHBs were 2.1 times more likely to have an ORC (95% CI = 1.40–3.38); and Hispanics were 2.5 times more likely (95% CI = 1.39–4.77). For every 1-year unit increase in age, the odds of ORC increased by 3% (95% CI = 1.00–1.05). CONCLUSIONS: Among NHANES participants with MetS, the prevalence of ORCs was significantly higher in NHBs and Hispanics, females, and older adults with MetS. Future studies, by race/ethnicity, are warranted on mortality risk of persons with MetS and ORC.
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spelling pubmed-80260662021-04-15 Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome Monestime, Shanada Beech, Bettina Kermah, Dulcie Norris, Keith PLoS One Research Article BACKGROUND: Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race/ethnicity. The purpose of this study was to compare the prevalence and predictors of ORCs by race/ethnicity among adults (>18) with MetS. METHODS: This was a retrospective, cross-sectional study using data from the 1999–2014 National Health and Nutrition Examination Survey (NHANES). A chi-square test was performed to determine differences in ORC prevalence between non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic participants with MetS. A multivariate logistic regression was used to evaluate predictors (race, sex, income, insurance, education, marital status, and smoking status) of ORC among adults with MetS. RESULTS: Of the 1,554 adults, the prevalence of ORC was 30.6% among NHWs, 51.3% in NHBs, and 54.1% in Hispanics (p = <0.001). Females were 6.27 times more likely to have an ORC compared to males (95% CI = 4.95–14.11). Compared to NHWs, NHBs were 2.1 times more likely to have an ORC (95% CI = 1.40–3.38); and Hispanics were 2.5 times more likely (95% CI = 1.39–4.77). For every 1-year unit increase in age, the odds of ORC increased by 3% (95% CI = 1.00–1.05). CONCLUSIONS: Among NHANES participants with MetS, the prevalence of ORCs was significantly higher in NHBs and Hispanics, females, and older adults with MetS. Future studies, by race/ethnicity, are warranted on mortality risk of persons with MetS and ORC. Public Library of Science 2021-04-07 /pmc/articles/PMC8026066/ /pubmed/33826671 http://dx.doi.org/10.1371/journal.pone.0249188 Text en © 2021 Monestime et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Monestime, Shanada
Beech, Bettina
Kermah, Dulcie
Norris, Keith
Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
title Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
title_full Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
title_fullStr Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
title_full_unstemmed Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
title_short Prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
title_sort prevalence and predictors of obesity-related cancers among racial/ethnic groups with metabolic syndrome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026066/
https://www.ncbi.nlm.nih.gov/pubmed/33826671
http://dx.doi.org/10.1371/journal.pone.0249188
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