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Matrix Metalloproteinase-9 (MMP-9) induced disruption of intestinal epithelial tight junction barrier is mediated by NF-κB activation

BACKGROUND: Matrix Metalloproteinase-9 (MMP-9) has been shown to play a key role in mediating inflammation and tissue damage in inflammatory bowel disease (IBD). In patients with IBD, the intestinal tight junction (TJ) barrier is compromised as characterized by an increase in intestinal permeability...

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Detalles Bibliográficos
Autores principales:	Al-Sadi, Rana, Engers, Jessica, Haque, Mohammad, King, Steven, Al-Omari, Deemah, Ma, Thomas Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026081/ https://www.ncbi.nlm.nih.gov/pubmed/33826658 http://dx.doi.org/10.1371/journal.pone.0249544

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