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Phospholipase A(2) inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression
Treating osteoarthritis (OA) remains a major clinical challenge. Despite recent advances in drug discovery and development, no disease-modifying drug for knee OA has emerged with any notable clinical success, in part, due to the lack of valid and responsive therapeutic targets and poor drug delivery...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026133/ https://www.ncbi.nlm.nih.gov/pubmed/33827816 http://dx.doi.org/10.1126/sciadv.abe6374 |