Phospholipase A(2) inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression

Treating osteoarthritis (OA) remains a major clinical challenge. Despite recent advances in drug discovery and development, no disease-modifying drug for knee OA has emerged with any notable clinical success, in part, due to the lack of valid and responsive therapeutic targets and poor drug delivery...

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Detalles Bibliográficos
Autores principales: Wei, Yulong, Yan, Lesan, Luo, Lijun, Gui, Tao, Jang, Biang, Amirshaghaghi, Ahmad, You, Tianyan, Tsourkas, Andrew, Qin, Ling, Cheng, Zhiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026133/
https://www.ncbi.nlm.nih.gov/pubmed/33827816
http://dx.doi.org/10.1126/sciadv.abe6374

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