Cargando…

NanoSINC-seq dissects the isoform diversity in subcellular compartments of single cells

Alternative mRNA isoforms play a key role in generating diverse protein isoforms. To dissect isoform usage in the subcellular compartments of single cells, we introduced an novel approach, nanopore sequencing coupled with single-cell integrated nuclear and cytoplasmic RNA sequencing, that couples mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Oguchi, Yusuke, Ozaki, Yuka, Abdelmoez, Mahmoud N., Shintaku, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026137/
https://www.ncbi.nlm.nih.gov/pubmed/33827812
http://dx.doi.org/10.1126/sciadv.abe0317