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NanoSINC-seq dissects the isoform diversity in subcellular compartments of single cells
Alternative mRNA isoforms play a key role in generating diverse protein isoforms. To dissect isoform usage in the subcellular compartments of single cells, we introduced an novel approach, nanopore sequencing coupled with single-cell integrated nuclear and cytoplasmic RNA sequencing, that couples mi...
Autores principales: | Oguchi, Yusuke, Ozaki, Yuka, Abdelmoez, Mahmoud N., Shintaku, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026137/ https://www.ncbi.nlm.nih.gov/pubmed/33827812 http://dx.doi.org/10.1126/sciadv.abe0317 |
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