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IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis

Ventilation throughout life is dependent on the formation of pulmonary alveoli, which create an extensive surface area in which the close apposition of respiratory epithelium and endothelial cells of the pulmonary microvascular enables efficient gas exchange. Morphogenesis of the alveoli initiates a...

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Detalles Bibliográficos
Autores principales: He, Hua, Snowball, John, Sun, Fei, Na, Cheng-Lun, Whitsett, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026181/
https://www.ncbi.nlm.nih.gov/pubmed/33591952
http://dx.doi.org/10.1172/jci.insight.144863