Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

BACKGROUND: Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β(3)-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this was accompanied by improved glucose metabolism. He...

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Detalles Bibliográficos
Autores principales: Finlin, Brian S., Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L., Vekaria, Hemendra J., El Khouli, Riham H., Johnson, Zachary R., Westgate, Philip M., Chen, Jianzhong, Morris, Andrew J., Sullivan, Patrick G., Dupont-Versteegden, Esther E., Kern, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026187/
https://www.ncbi.nlm.nih.gov/pubmed/33571166
http://dx.doi.org/10.1172/jci.insight.143650

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