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Targeted DNA methylation profiling reveals epigenetic signatures in peanut allergy

DNA methylation (DNAm) has been shown to play a role in mediating food allergy; however, the mechanism by which it does so is poorly understood. In this study, we used targeted next-generation bisulfite sequencing to evaluate DNAm levels in 125 targeted highly informative genomic regions containing...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoying, Han, Xiaorui, Lyu, Shu-Chen, Bunning, Bryan, Kost, Laurie, Chang, Iris, Cao, Shu, Sampath, Vanitha, Nadeau, Kari C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026193/
https://www.ncbi.nlm.nih.gov/pubmed/33571165
http://dx.doi.org/10.1172/jci.insight.143058