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Versatile workflow for cell type–resolved transcriptional and epigenetic profiles from cryopreserved human lung

Complexity of lung microenvironment and changes in cellular composition during disease make it exceptionally hard to understand molecular mechanisms driving development of chronic lung diseases. Although recent advances in cell type–resolved approaches hold great promise for studying complex disease...

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Detalles Bibliográficos
Autores principales: Llamazares-Prada, Maria, Espinet, Elisa, Mijošek, Vedrana, Schwartz, Uwe, Lutsik, Pavlo, Tamas, Raluca, Richter, Mandy, Behrendt, Annika, Pohl, Stephanie T., Benz, Naja P., Muley, Thomas, Warth, Arne, Heußel, Claus Peter, Winter, Hauke, Landry, Jonathan J. M., Herth, Felix J.F., Mertens, Tinne C.J., Karmouty-Quintana, Harry, Koch, Ina, Benes, Vladimir, Korbel, Jan O., Waszak, Sebastian M., Trumpp, Andreas, Wyatt, David M., Stahl, Heiko F., Plass, Christoph, Jurkowska, Renata Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026197/
https://www.ncbi.nlm.nih.gov/pubmed/33630765
http://dx.doi.org/10.1172/jci.insight.140443