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Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia
Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders (FGIDs) and account for a large proportion of consulting patients. These 2 disorders overlap with each other frequently. The pathogenesis of IBS or FD is complicated and multi-factors relate...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Society of Neurogastroenterology and Motility
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026374/ https://www.ncbi.nlm.nih.gov/pubmed/33795538 http://dx.doi.org/10.5056/jnm20175 |
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author | Wang, Congzhen Fang, Xiucai |
author_facet | Wang, Congzhen Fang, Xiucai |
author_sort | Wang, Congzhen |
collection | PubMed |
description | Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders (FGIDs) and account for a large proportion of consulting patients. These 2 disorders overlap with each other frequently. The pathogenesis of IBS or FD is complicated and multi-factors related, in which infectious or non-infectious inflammation and local or systemic immune response play significant roles. There are few studies focusing on the mechanism of inflammation in patients with overlap syndrome of irritable bowel syndrome and functional dyspepsia (IBS-FD). This review focuses on current advances about the role of inflammation in the pathogenesis of IBS and FD and the possible mechanism of inflammation in IBS-FD. |
format | Online Article Text |
id | pubmed-8026374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Society of Neurogastroenterology and Motility |
record_format | MEDLINE/PubMed |
spelling | pubmed-80263742021-04-30 Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia Wang, Congzhen Fang, Xiucai J Neurogastroenterol Motil Review Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders (FGIDs) and account for a large proportion of consulting patients. These 2 disorders overlap with each other frequently. The pathogenesis of IBS or FD is complicated and multi-factors related, in which infectious or non-infectious inflammation and local or systemic immune response play significant roles. There are few studies focusing on the mechanism of inflammation in patients with overlap syndrome of irritable bowel syndrome and functional dyspepsia (IBS-FD). This review focuses on current advances about the role of inflammation in the pathogenesis of IBS and FD and the possible mechanism of inflammation in IBS-FD. The Korean Society of Neurogastroenterology and Motility 2021-04-30 2021-04-30 /pmc/articles/PMC8026374/ /pubmed/33795538 http://dx.doi.org/10.5056/jnm20175 Text en © 2021 The Korean Society of Neurogastroenterology and Motility https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Wang, Congzhen Fang, Xiucai Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia |
title | Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia |
title_full | Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia |
title_fullStr | Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia |
title_full_unstemmed | Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia |
title_short | Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia |
title_sort | inflammation and overlap of irritable bowel syndrome and functional dyspepsia |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026374/ https://www.ncbi.nlm.nih.gov/pubmed/33795538 http://dx.doi.org/10.5056/jnm20175 |
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