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Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis

The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic...

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Autores principales: Cundari, Giulia, Galea, Nicola, De Rubeis, Gianluca, Frustaci, Andrea, Cilia, Francesco, Mancuso, Giuseppe, Marchitelli, Livia, Catapano, Federica, Carbone, Iacopo, Catalano, Carlo, Francone, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026431/
https://www.ncbi.nlm.nih.gov/pubmed/33190198
http://dx.doi.org/10.1007/s10554-020-02097-9
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author Cundari, Giulia
Galea, Nicola
De Rubeis, Gianluca
Frustaci, Andrea
Cilia, Francesco
Mancuso, Giuseppe
Marchitelli, Livia
Catapano, Federica
Carbone, Iacopo
Catalano, Carlo
Francone, Marco
author_facet Cundari, Giulia
Galea, Nicola
De Rubeis, Gianluca
Frustaci, Andrea
Cilia, Francesco
Mancuso, Giuseppe
Marchitelli, Livia
Catapano, Federica
Carbone, Iacopo
Catalano, Carlo
Francone, Marco
author_sort Cundari, Giulia
collection PubMed
description The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic resonance (CMR) on a 1.5 T scanner. Protocol included cine-SSFP, T2-weighted STIR, T2 mapping, early and late gadolinium enhancement and T1 mapping acquired before and after gadolinium administration. The degree of agreement has been calculated with Cohen’s K test. 42 patients also underwent endomyocardial biopsy (EMB). IL onset was present in 54/102 patients, CM in 28/102 and AR in 20/102. nLLC were positive in 58.3% of the patients, while oLLC in 37.9%, k = 0.57 (IC: 0.428–0.713). The degree of agreement between nLLC and oLLC was 0.49 (IC: 0.111–0.876) for AR onset (nLLC positive in 35% vs oLLC in 15%), 0.25 (IC: 0.035–0.459) for CM pattern (nLLC positive in 60.7% vs oLLC 17.9%) and 0.73 (IC: 0.543–0.912) for IL presentation (nLLC positive in 66.7% vs oLLC in 57.4%). Diagnostic accuracy was 75% for both nLLC and oLLC among IL onset, and 41.6% for oLLC vs 66.7% for nLLC, as regards CM clinical presentation. nLLC have improved diagnostic performance of CMR for the diagnosis of acute myocarditis, in particular for atypical clinical presentation.
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spelling pubmed-80264312021-04-26 Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis Cundari, Giulia Galea, Nicola De Rubeis, Gianluca Frustaci, Andrea Cilia, Francesco Mancuso, Giuseppe Marchitelli, Livia Catapano, Federica Carbone, Iacopo Catalano, Carlo Francone, Marco Int J Cardiovasc Imaging Original Paper The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic resonance (CMR) on a 1.5 T scanner. Protocol included cine-SSFP, T2-weighted STIR, T2 mapping, early and late gadolinium enhancement and T1 mapping acquired before and after gadolinium administration. The degree of agreement has been calculated with Cohen’s K test. 42 patients also underwent endomyocardial biopsy (EMB). IL onset was present in 54/102 patients, CM in 28/102 and AR in 20/102. nLLC were positive in 58.3% of the patients, while oLLC in 37.9%, k = 0.57 (IC: 0.428–0.713). The degree of agreement between nLLC and oLLC was 0.49 (IC: 0.111–0.876) for AR onset (nLLC positive in 35% vs oLLC in 15%), 0.25 (IC: 0.035–0.459) for CM pattern (nLLC positive in 60.7% vs oLLC 17.9%) and 0.73 (IC: 0.543–0.912) for IL presentation (nLLC positive in 66.7% vs oLLC in 57.4%). Diagnostic accuracy was 75% for both nLLC and oLLC among IL onset, and 41.6% for oLLC vs 66.7% for nLLC, as regards CM clinical presentation. nLLC have improved diagnostic performance of CMR for the diagnosis of acute myocarditis, in particular for atypical clinical presentation. Springer Netherlands 2020-11-15 2021 /pmc/articles/PMC8026431/ /pubmed/33190198 http://dx.doi.org/10.1007/s10554-020-02097-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Paper
Cundari, Giulia
Galea, Nicola
De Rubeis, Gianluca
Frustaci, Andrea
Cilia, Francesco
Mancuso, Giuseppe
Marchitelli, Livia
Catapano, Federica
Carbone, Iacopo
Catalano, Carlo
Francone, Marco
Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
title Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
title_full Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
title_fullStr Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
title_full_unstemmed Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
title_short Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
title_sort use of the new lake louise criteria improves cmr detection of atypical forms of acute myocarditis
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026431/
https://www.ncbi.nlm.nih.gov/pubmed/33190198
http://dx.doi.org/10.1007/s10554-020-02097-9
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