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Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis
The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026431/ https://www.ncbi.nlm.nih.gov/pubmed/33190198 http://dx.doi.org/10.1007/s10554-020-02097-9 |
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author | Cundari, Giulia Galea, Nicola De Rubeis, Gianluca Frustaci, Andrea Cilia, Francesco Mancuso, Giuseppe Marchitelli, Livia Catapano, Federica Carbone, Iacopo Catalano, Carlo Francone, Marco |
author_facet | Cundari, Giulia Galea, Nicola De Rubeis, Gianluca Frustaci, Andrea Cilia, Francesco Mancuso, Giuseppe Marchitelli, Livia Catapano, Federica Carbone, Iacopo Catalano, Carlo Francone, Marco |
author_sort | Cundari, Giulia |
collection | PubMed |
description | The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic resonance (CMR) on a 1.5 T scanner. Protocol included cine-SSFP, T2-weighted STIR, T2 mapping, early and late gadolinium enhancement and T1 mapping acquired before and after gadolinium administration. The degree of agreement has been calculated with Cohen’s K test. 42 patients also underwent endomyocardial biopsy (EMB). IL onset was present in 54/102 patients, CM in 28/102 and AR in 20/102. nLLC were positive in 58.3% of the patients, while oLLC in 37.9%, k = 0.57 (IC: 0.428–0.713). The degree of agreement between nLLC and oLLC was 0.49 (IC: 0.111–0.876) for AR onset (nLLC positive in 35% vs oLLC in 15%), 0.25 (IC: 0.035–0.459) for CM pattern (nLLC positive in 60.7% vs oLLC 17.9%) and 0.73 (IC: 0.543–0.912) for IL presentation (nLLC positive in 66.7% vs oLLC in 57.4%). Diagnostic accuracy was 75% for both nLLC and oLLC among IL onset, and 41.6% for oLLC vs 66.7% for nLLC, as regards CM clinical presentation. nLLC have improved diagnostic performance of CMR for the diagnosis of acute myocarditis, in particular for atypical clinical presentation. |
format | Online Article Text |
id | pubmed-8026431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-80264312021-04-26 Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis Cundari, Giulia Galea, Nicola De Rubeis, Gianluca Frustaci, Andrea Cilia, Francesco Mancuso, Giuseppe Marchitelli, Livia Catapano, Federica Carbone, Iacopo Catalano, Carlo Francone, Marco Int J Cardiovasc Imaging Original Paper The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic resonance (CMR) on a 1.5 T scanner. Protocol included cine-SSFP, T2-weighted STIR, T2 mapping, early and late gadolinium enhancement and T1 mapping acquired before and after gadolinium administration. The degree of agreement has been calculated with Cohen’s K test. 42 patients also underwent endomyocardial biopsy (EMB). IL onset was present in 54/102 patients, CM in 28/102 and AR in 20/102. nLLC were positive in 58.3% of the patients, while oLLC in 37.9%, k = 0.57 (IC: 0.428–0.713). The degree of agreement between nLLC and oLLC was 0.49 (IC: 0.111–0.876) for AR onset (nLLC positive in 35% vs oLLC in 15%), 0.25 (IC: 0.035–0.459) for CM pattern (nLLC positive in 60.7% vs oLLC 17.9%) and 0.73 (IC: 0.543–0.912) for IL presentation (nLLC positive in 66.7% vs oLLC in 57.4%). Diagnostic accuracy was 75% for both nLLC and oLLC among IL onset, and 41.6% for oLLC vs 66.7% for nLLC, as regards CM clinical presentation. nLLC have improved diagnostic performance of CMR for the diagnosis of acute myocarditis, in particular for atypical clinical presentation. Springer Netherlands 2020-11-15 2021 /pmc/articles/PMC8026431/ /pubmed/33190198 http://dx.doi.org/10.1007/s10554-020-02097-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Original Paper Cundari, Giulia Galea, Nicola De Rubeis, Gianluca Frustaci, Andrea Cilia, Francesco Mancuso, Giuseppe Marchitelli, Livia Catapano, Federica Carbone, Iacopo Catalano, Carlo Francone, Marco Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis |
title | Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis |
title_full | Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis |
title_fullStr | Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis |
title_full_unstemmed | Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis |
title_short | Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis |
title_sort | use of the new lake louise criteria improves cmr detection of atypical forms of acute myocarditis |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026431/ https://www.ncbi.nlm.nih.gov/pubmed/33190198 http://dx.doi.org/10.1007/s10554-020-02097-9 |
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