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How useful can the Voigt profile be in protein folding processes?

The analytical expression for the Voigt profile, along with its simplified forms for the Gaussian and Lorentzian dominance, is presented. The applicability of the Voigt profile in the description of anomalous diffusion phenomena, ubiquitous in different fields of science including protein folding, i...

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Detalles Bibliográficos
Autores principales: Maisuradze, Luka, Maisuradze, Gia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026557/
https://www.ncbi.nlm.nih.gov/pubmed/33398661
http://dx.doi.org/10.1007/s10930-020-09954-5
Descripción
Sumario:The analytical expression for the Voigt profile, along with its simplified forms for the Gaussian and Lorentzian dominance, is presented. The applicability of the Voigt profile in the description of anomalous diffusion phenomena, ubiquitous in different fields of science including protein folding, is discussed. It is shown that the Voigt profile is a good descriptor of the processes occurring in protein folding and in the native state. The usefulness of the Voigt profile in deriving important information of the diffusive motions in proteins from a quasielastic incoherent neutron scattering experiments is illustrated.